Tuesday, August 28, 2007

Genetic insertion

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Genetic insertion

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An illustration of an insertion at chromosome level
An illustration of an insertion at chromosome level

Genetic Insertion is the addition of one or more nucleotide base pairs into a genetic sequence. This can often happen in microsatellite regions due to the DNA polymerase slipping.

On a chromosome level, an insertion refers to the insertion of a larger sequence into a chromosome. This can happen due to unequal crossover during meiosis.

N region addition is the addition of non-coded nucleotides during recombination by terminal deoxynucleotidyl transferase.

P nucleotide insertion is the insertion of palindromic sequences encoded by the ends of the recombining gene segments.

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